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内容简介
“司美格鲁肽”,在国内是一款用于治疗糖尿病的药物。不过,在不少社交平台,这款药物,被捧为了“减肥”神药,号称“不用节食不用锻炼,躺着一动不动就能减肥。”这款药物,真的有那么神吗? 49岁的吴阿姨,在20多岁时,就确诊患有2型糖尿病。近20年来,一直靠注射胰岛素来控制血糖,血糖控制得还算不错,但体重却有些失控,今年初,在医生的指导下,吴阿姨开始使用“司美格鲁肽注射液”,半年下来,血糖和尿蛋白的指标降下来了,体重也减轻了。“最胖的时候,140多斤,用了这个药之后瘦了十几斤,就是胃口一直不怎么好了。”吴阿姨直言道。 然而,去年下半年以来,吴阿姨却发现,想要配药时,医院有时会出现这款注射液“断货”的情况,甚至断货在不止一家医院都有发生。 医生介绍,司美格鲁肽这类药物,可以模拟一种肠促胰岛素激素的作用,从而降低血糖水平,同时增加饱腹感,用于治疗2型糖尿病已经超过15年。然而,也就是因为它有一定的减重和控制食欲的功效,这段时间,突然在网络上“爆红”了起来。社交平台上不时有人提及一些海外名人用后的直观效果,让不少国内消费者心动不已,认为这是一款减肥神药。同济大学附属第十人民医院内分泌代谢科主任陈海冰告诉记者:“有很多爱美人士到医院来配,实际上是挤兑了真正需要治疗的一部分患者的药物来源。” 与国外的口服液不同,目前国内的司美格鲁肽都是注射针剂,且并未获批“减重”适应症,但是,依然不断有网友在线上求购此药。专家指出,目前国内临床上将“司美格鲁肽”用于减重治疗的,往往都是大体重患者,在切胃手术术前使用,目的是为了降低手术的风险。“400斤、500斤的患者,这种手术风险是非常大的,这个药打上两个月以后,体重或许会下降一些,对手术风险就小多了。”第十人民医院减重外科教授朱江帆解释道 而一般情况如果自行随意用药,并非都能实现向往中的快速减重效果,甚至还可能出现一些副作用。28岁的常小姐,体重206斤,前两天,刚做完腹腔镜切胃手术,常小姐想用“司美格鲁肽”来巩固减重,但医生表示,对于还在术后康复的她来说,并不合适。“体重下降不了很多的,这药肯定是有副作用的,胃肠道的不舒服。”第十人民医院减重外科教授朱江帆说道。 70多岁的罗老伯,从今年2月初,就开始注射“司美格鲁肽”降糖,4个多月下来,体重也没有下降一斤。东方医院北院内分泌科副主任宋君对此解释称:“从减重的角度上来说,它是有个体差异的。” 其实,此前就有研究表明,许多人在停止注射后很快体重就会反弹。专家介绍,“司美格鲁肽”是否对患者有效,需要在用药前,进行第二代GLP-1受体的基因检测。而如果未经基因检验程序、不遵医嘱地注射“司美格鲁肽”,减重没有效果也许还算是小问题,严重时,可能会引一系列的不良反应。 东方医院药学部主任马雅斌表示:“使用常规剂量的司美格鲁肽注射液时,发生胃肠道反应的发生率高达84.1%,严重不良反应包括甲状腺细胞肿瘤、低血糖伴同时使用胰岛素促分泌剂或胰岛素,胰腺炎、急性胆囊炎,糖尿病视网膜病变并发症,急性肾损伤及全身性过敏反应。” 医生提醒市民,切勿看了社交媒体上的各种帖子,就自行胡乱用药,还是务必遵照医嘱,以免得不偿失。 不少爱美人士通过代购购买所谓来自欧洲、香港等地区的“司美格鲁肽”,这里也要提醒,这类药品真假难辨,存在安全隐患。医生也提醒,无论是司美格鲁肽还是其他的药品,一定要在专业人员的指导下用药,切勿为了减重而损害了健康。 (看看新闻Knews记者:潘窈窈 摄像:王毅 编辑:由由酱) 举报/反馈